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Radioprotection

Dioxinodehydroeckol protects human keratinocyte cells from UVB-induced apoptosis modulated by related genes Bax/Bcl-2 and caspase pathway.
Ryu B, Ahn BN, Kang KH, Kim YS, Li YX, Kong CS, Kim SK, Kim DG.
J Photochem Photobiol B. 2015, 153, 352-357.

Phloroglucinol inhibits ultraviolet B radiation-induced oxidative stress in the mouse skin. br> Piao MJ, Ahn MJ, Kang KA, Kim KC, Zheng J, Yao CW, Cha JW, Hyun CL, Kang HK, Lee NH, Hyun JW.
Int J Radiat Biol. 2014, 90(10), 928-935.

Antioxidant marine algae phlorotannins and radioprotection: A review of experimental evidence.
Shin T, Ahn M, Hyun JW, Kim SH, Moon C.
Acta Histochem. 2014, 116(5), 669-674.

Phloroglucinol protects small intestines of mice from ionizing radiation by regulating apoptosis-related molecules: a comparative immunohistochemical study.
Ha D, Bing SJ, Cho J, Ahn G, Kim DS, Al-Amin M, Park SJ, Jee Y.
J Histochem Cytochem. 2013, 61(1), 63-74.

Radio-protective effect of polysaccharides isolated from Lactobacillus brevis-fermented Ecklonia cava.
Lee W, Ahn G, Lee BJ, Wijesinghe WA, Kim D, Yang H, Kim YM, Park SJ, Jee Y, Jeon YJ.
Int J Biol Macromol. 2013, 52, 260-266.

Photo-oxidative stress by ultraviolet-B radiation and antioxidative defense of eckstolonol in human keratinocytes.
Jang J, Ye BR, Heo SJ, Oh C, Kang DH, Kim JH, Affan A, Yoon KT, Choi YU, Park SC, Han S, Qian ZJ, Jung WK, Choi IW.
Environ Toxicol Pharmacol. 2012, 34(3), 926-934.

Protective effects of phlorotannins against ultraviolet B radiation in zebrafish (Danio rerio).
Cha SH, Ko CI, Kim D, Jeon YJ.
Vet Dermatol. 2012, 23(1), 51-56.

Phloroglucinol (PG) purified from Ecklonia cava attenuates radiation-induced apoptosis in blood lymphocytes and splenocytes. Park SJ, Ahn G, Lee NH, Park JW, Jeon YJ, Jee Y.
Food Chem Toxicol. 2011, 49(9), 2236-2242.

Dieckol rescues mice from lethal irradiation by accelerating hemopoiesis and curtailing immunosuppression.
Park E, Ahn G, Yun JS, Kim MJ, Bing SJ, Kim DS, Lee J, Lee NH, Park JW, Jee Y.
Int J Radiat Biol. 2010, 86(10), 848-859.

Phloroglucinol (1,3,5-trihydroxybenzene) protects against ionizing radiation-induced cell damage through inhibition of oxidative stress in vitro and in vivo.
Kang KA, Zhang R, Chae S, Lee SJ, Kim J, Kim J, Jeong J, Lee J, Shin T, Lee NH, Hyun JW.
Chem Biol Interact. 2010, 185(3), 215-226.

MMT Inhibitory Action of Seanol.
Saeki Y, NishiuraH, Tanaka K.
Fragrance J. 2009, 37, 94-96.

Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation.
Heo SJ, Ko SC, Cha SH, Kang DH, Park HS, Choi YU, Kim D, Jung WK, Jeon YJ.
Toxicol In Vitro. 2009, 23(6), 1123-1130.

Eckol protects V79-4 lung fibroblast cells against γ-ray radiation-induced apoptosis via the scavenging of reactive oxygen species and inhibiting of the c-Jun NH2-terminal kinase pathway.
Zhang R, Kang KA, Piao MJ, Ko DO, Wang ZH, Lee IK, Kim BJ, Jeong IY, Shin T, Park JW, Lee NH, Hyun JW.
Eur J Pharm. 2008, 591(1-3), 114-123.

Modulation of apoptosis of eckol against ionizing radiation in mice.
Park E, Lee NH, Joo HG, Jee Y.
Biochem Biophys Res Commun. 2008, 372(4), 792-797.

Radioprotective properties of eckol against ionizing radiation in mice.
Park E, Ahn GN, Lee NH, Kim JM, Yun JS, Hyun JW, Jeon YJ, Wie MB, Lee YJ, Park JW, Jee Y.
FEBS Lett. 2008, 582(6), 925-930.

Protective effect of phlorotannin components phlorogluciol and eckol on radiation- induced intestinal injury in mice.
Moon CM, Kim SH, Kim JC, Hyun JW, Lee NH, Park JW, Shin T.
Phytother Res. 2008, 22(2), 238-242.

Protective effect of triphlorethol-A from Ecklonia cava against ionizing radiation in vitro.
Kang KA, Zhang R, Lee KH, Chae S, Kim BJ, Kwak YS, Park JW, Lee NH, Hyun JW.
J Radiat Res. 2006, 47(1), 61-68.

Photochemoprevention of UVB-induced skin carcinogenesis in SKH-1 mice by brown algae polyphenols.
Hwang H, Chen T, Nines RG, Shin HC, Stoner GD.
Int J Cancer . 2006, 119(12), 2742-2749.

Suppression of iNOS expression by phlorotannins in chronic exposure of skin to UVB radiation.
Hwang H, Chen T, Stoner GD, Lee KB, Yoo YC, Shin HC.
Lab Anim Res. 2005, 21(4), 385-389.